FAST-2 mouse

eagle-i ID

Resource Type

Properties

1. Resource Description

   Used to study alcoholism; enhanced locomotor stimulant response to alcohol. Cryopreserved. Selectively bred line.

2. Contact

   Metten, Pamela, Ph.D.

3. Inventory Number

   MMRRC:029990-UCD

4. Related Disease

   alcohol abuse

5. Related Publication or Documentation

   Response to selection for ethanol-induced locomotor activation: genetic analyses and selection response characterization

6. Website(s)

   http://www.mmrrc.org/catalog/StrainCatalogSearchForm.jsp

7. Website(s)

   http://www.ohsu.edu/parc/animal_models.htm

8. Related Technique

   Behavioral assay

9. Parental Strain Name

   HS/Ibg 8-way inbred strain cross

10. Biological process studied

    Behavioral response to ethanol

11. Phenotype Findings

    Heightened sensitivity to the locomotor activating effects of a single 2.0 g/kg IP injection of ethanol, compared to response after saline injection.

12. Location

    Portland Alcohol Research Center