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IWSR-1 mouse
eagle-i ID
http://ohsu.eagle-i.net/i/0000012a-25c4-4310-ba9b-9bad8000000c
Resource Type
Properties
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Resource Description
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Used to study alcoholism; reduced withdrawal convulsions after chronic dependence on alcohol. Inbred strain from Withdrawal Seizure Resistant - 1. Fully inbred, derived from selectively bred line. Live mice are available.
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Contact
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Metten, Pamela, Ph.D.
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Related Disease
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alcohol abuse
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Related Publication or Documentation
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Bidirectional Selection for Susceptibility to Ethanol Withdrawal Seizures in Mus musculus
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Website(s)
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http://www.ohsu.edu/parc/animal_models.htm
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Related Technique
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Behavioral assay
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Parental Strain Name
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HS/Ibg 8-way inbred strain cross
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Phenotype Findings
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Display mild handling-induced convulsions after withdrawal from chronic ethanol vapor inhalation.
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Location
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Portland Alcohol Research Center