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COLD-2 mouse
eagle-i ID
http://ohsu.eagle-i.net/i/0000012a-25c4-4310-ba9b-9bad80000011
Resource Type
Properties
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Resource Description
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Used to study alcoholism; alcohol-induced hypothermia test. Shows profound hypothermia. Embryo cryopreserved. Selectively bred line.
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Contact
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Metten, Pamela, Ph.D.
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Related Disease
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alcohol abuse
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Related Publication or Documentation
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Genetic selection of mouse lines sensitive (COLD) and resistant (HOT) to acute ethanol hypothermia
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Website(s)
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http://www.ohsu.edu/parc/animal_models.htm
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Related Technique
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Behavioral assay
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Parental Strain Name
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HS/Ibg 8-way inbred strain cross
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Phenotype Findings
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Extreme hypothermia 30-60 minutes after 3 g/kg ethanol.
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Location
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Portland Alcohol Research Center