Endometrial biopsy protocol

eagle-i ID

Resource Type

Properties

1. Resource Description

   Collection of Endometrial biopsies: The subject will be placed in lithotomy on a GYN examination table and a bimanual exam will be performed to confirm uterine position. An Explora (CooperSurgical or similar) FDA-approved vacuum suction biopsy device will be used to collect all samples using standard technique described as follows: Following an antiseptic wash (betadine or hibiclens) of the cervix, the biopsy curette will be passed through the cervix to the uterine fundus, the vacuum syringe will be attached, and a brief curettage preformed. For analgesia, subjects may elect to receive intrauterine lidocaine 2% solution, 5cc, delivered through the biopsy curette prior to the curettage procedure. If the curette cannot be passed easily, a paracervical block of 1% lidocaine (10 cc) will be administered, followed by placement of a tenaculum, and sequential cervical dilation as needed. Following collection, the specimen samples will immediately be placed in formalin and transported to the location specified in the protocol for further processing.

2. Contact

   Bespflug, Tracy

3. Uses

   Clinical monitoring

4. Used by

   Women's Health Research Unit

5. Author

   Jensen, Jeffrey T., M.D., M.P.H.