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Endometrial biopsy protocol

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Resource Type

  1. Protocol


  1. Resource Description
    Collection of Endometrial biopsies: The subject will be placed in lithotomy on a GYN examination table and a bimanual exam will be performed to confirm uterine position. An Explora (CooperSurgical or similar) FDA-approved vacuum suction biopsy device will be used to collect all samples using standard technique described as follows: Following an antiseptic wash (betadine or hibiclens) of the cervix, the biopsy curette will be passed through the cervix to the uterine fundus, the vacuum syringe will be attached, and a brief curettage preformed. For analgesia, subjects may elect to receive intrauterine lidocaine 2% solution, 5cc, delivered through the biopsy curette prior to the curettage procedure. If the curette cannot be passed easily, a paracervical block of 1% lidocaine (10 cc) will be administered, followed by placement of a tenaculum, and sequential cervical dilation as needed. Following collection, the specimen samples will immediately be placed in formalin and transported to the location specified in the protocol for further processing.
  2. Contact
    Bespflug, Tracy
  3. Uses
    Clinical monitoring
  4. Used by
    Women's Health Research Unit
  5. Author
    Jensen, Jeffrey T., M.D., M.P.H.
Provenance Metadata About This Resource Record
Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016