anti-TH

eagle-i ID

Resource Type

Properties

1. Resource Description

   "Tyrosine hydroxylase plays an important role in the physiology of adrenergic neurons. It is the first and rate-limiting enzyme involved in the biosynthesis of the catecholamines Dopamine and Norepinephrine from tyrosine. TH is, therefore, a useful marker for dopaminergic and noradrenergic neurons. The enzymatic activity of TH requires ferrous ions as cofactors and is believed to be regulated by phosphorylation. At least four isoforms of human TH have been identified which result from alternative splicing."

2. Additional Name

   anti-Tyrosine Hydroxylase

3. Contact

   Habecker, Beth, Ph.D.

4. Manufacturer

   Millipore Corporation

5. Related Publication or Documentation

   Cardiac ischemia-reperfusion regulates sympathetic neuropeptide expression through gp130-dependent and independent mechanisms.

6. Related Publication or Documentation

   Heart immunohistochemistry protocol

7. Website(s)

   http://www.millipore.com/catalogue/item/ab152

8. Related Technique

   Immunohistochemistry assay

9. Species Reactivity

   0000012f-2864-94c4-f561-6e8a80000000

10. Immunogenic Material

    Denatured tyrosine hydroxylase from rat pheochromocytoma (denatured by sodium dodecyl sulfate).

11. Source Organism Type

    Oryctolagus cuniculus

12. Antibody Registry ID

    AB_390204

13. Catalog Number

    AB152

14. Antibody Target(s)

    Tyrosine hydroxylase

15. Related Technique

    Immunohistochemistry assay

16. Location

    Beth A. Habecker Laboratory