Murine arterial thrombosis model

eagle-i ID

Resource Type

Properties

1. Resource Description

   Model used to study thrombosis formation in mouse models. Thrombus formation induced by ferric chloride or laser injury.

2. Uses

   FXI+/+ mice

3. Uses

   FXI-/- mice

4. Uses

   GE-400T gamma scintillation camera

5. Uses

   Neutralizing monoclonal IgG 14E11 to mammalian factor XI

6. Uses

   Western blot analysis

7. Used by

   Andras Gruber Laboratory

8. Author

   Gruber, Andras, M.D.

9. Topic

   vascular disease

10. Related Publication or Documentation

    A role for factor XIIa–mediated factor XI activation in thrombus formation in vivo