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Neutralizing monoclonal IgG O1A6 to human factor XI

eagle-i ID

http://ohsu.eagle-i.net/i/0000012f-6fac-eb01-f561-6e8a80000000

Resource Type

  1. Monoclonal antibody reagent

Properties

  1. Resource Description
    Antibody binds to the A3 domain of human fXI and interferes with activation of factor IX by fXIa.
  2. Manufacturer
    Gruber, Andras, M.D.
  3. Related Publication or Documentation
    A role for factor XIIa–mediated factor XI activation in thrombus formation in vivo
  4. Related Publication or Documentation
    Factor XI contributes to thrombin generation in the absence of factor XII.
  5. Related Technique
    Western blot analysis
  6. Species Reactivity
    0000012f-2861-6fb1-f561-6e8a80000000
  7. Immunogenic Material
    Factor XI
  8. Isotype
    IgG
  9. Source Organism Type
    Mus_musculus
  10. Antibody Registry ID
    AB_10013426
  11. Clone ID
    O1A6
  12. Antibody Target(s)
    A3 domain of human fXI
  13. Related Technique
    Western blot analysis
  14. Location
    Andras Gruber Laboratory
  15. recognizes_product_of_gene
    2160
 
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