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Neutralizing monoclonal IgG O1A6 to human factor XI
eagle-i ID
http://ohsu.eagle-i.net/i/0000012f-6fac-eb01-f561-6e8a80000000
Resource Type
Monoclonal antibody reagent
Properties
Resource Description
Antibody binds to the A3 domain of human fXI and interferes with activation of factor IX by fXIa.
Manufacturer
Gruber, Andras, M.D.
Related Publication or Documentation
A role for factor XIIa–mediated factor XI activation in thrombus formation in vivo
Related Publication or Documentation
Factor XI contributes to thrombin generation in the absence of factor XII.
Related Technique
Western blot analysis
Species Reactivity
0000012f-2861-6fb1-f561-6e8a80000000
Immunogenic Material
Factor XI
Isotype
IgG
Source Organism Type
Mus musculus
Antibody Registry ID
AB_10013426
Clone ID
O1A6
Antibody Target(s)
A3 domain of human fXI
Related Technique
Western blot analysis
Location
Andras Gruber Laboratory
recognizes_product_of_gene
2160
Inferred Types from the eagle-i Ontology (
What is an ontology?
)
entity
continuant
independent_continuant
material_entity
Reagent
Antibody reagent
processed material
Thing
Provenance Metadata About This Resource Record
workflow owner
nvasilevsky (Nicole Vasilevsky)
workflow state
Published
contributor
tjohnson (Tenille Johnson)
contributor
nvasilevsky (Nicole Vasilevsky)
created
2011-04-19T16:31:37.716-05:00
creator
nvasilevsky (Nicole Vasilevsky)
modified
2013-08-09T16:06:52.877-05:00