Neutralizing monoclonal IgG O1A6 to human factor XI

eagle-i ID

Resource Type

Properties

1. Resource Description

   Antibody binds to the A3 domain of human fXI and interferes with activation of factor IX by fXIa.

2. Manufacturer

   Gruber, Andras, M.D.

3. Related Publication or Documentation

   A role for factor XIIa–mediated factor XI activation in thrombus formation in vivo

4. Related Publication or Documentation

   Factor XI contributes to thrombin generation in the absence of factor XII.

5. Related Technique

   Western blot analysis

6. Species Reactivity

   0000012f-2861-6fb1-f561-6e8a80000000

7. Immunogenic Material

   Factor XI

8. Isotype

   IgG

9. Source Organism Type

   Mus musculus

10. Antibody Registry ID

    AB_10013426

11. Clone ID

    O1A6

12. Antibody Target(s)

    A3 domain of human fXI

13. Related Technique

    Western blot analysis

14. Location

    Andras Gruber Laboratory

15. recognizes_product_of_gene

    2160