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Oregon Health & Science UniversityOregon Health & Science University
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Neutralizing monoclonal IgG 14E11 to mammalian factor XI

eagle-i ID

http://ohsu.eagle-i.net/i/0000012f-6fad-09d0-f561-6e8a80000000

Resource Type

  1. Monoclonal antibody reagent

Properties

  1. Resource Description
    "Clone 14E11 was expanded in a CL1000 bioreactor (Integra Biosciences), and immunoglobulin G (IgG) was purified by cation exchange and thiophilic agarose chromatography. 14E11 was biotinylated using an EZ-link sulfo-NHS-biotinylation kit (Thermo Scientific)."
  2. Manufacturer
    Gruber, Andras, M.D.
  3. Related Publication or Documentation
    A role for factor XIIa–mediated factor XI activation in thrombus formation in vivo
  4. Related Technique
    Western blot analysis
  5. Immunogenic Material
    FXI
  6. Isotype
    IgG
  7. Source Organism Type
    Mus musculus
  8. Antibody Registry ID
    AB_10013426
  9. Clone ID
    14E11
  10. Conjugate
    Biotin
  11. Antibody Target(s)
    F11 coagulation factor XI
  12. Related Technique
    Western blot analysis
  13. Location
    Andras Gruber Laboratory
 
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The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016