Mus musculus
RFS-MycT58A+/-/LSL-KrasG12D
http://mouse.ncifcrf.gov/available_details.asp?ID=01XJ6
Website(s)
has URL
has_url
LSL-KrasG12D carry a latent point-mutant allele of Kras2 (K-rasG12D). Cre-mediated recombination leads to deletion of a transcriptional termination sequence (Lox-Stop-Lox) and expression of the oncogenic protein.
Resource Description
resource_description
ROSA Floxed Stop-MycT58A+/-/LSL-KrasG12D
Additional Name
eagle-i_synonym
Related Publication or Documentation
has documentation
has_documentation
Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse.
Related Disease
model of
model_of
cancer
Genetic Alteration(s)
has sequence alteration
has_sequence_alteration
LSL-KrasG12D
RFS-MycT58A
C57BL/6
Parental Strain Name
has parental strain name
has_parental_strain_name
B6.129
Developed by
resource_developed_by
Sears, Rosalie, Ph.D.
Location
located_in
Rosalie Sears Laboratory
located in
2012-11-29T11:50:31.399-06:00
nvasilevsky (Nicole Vasilevsky)
2015-08-17T14:51:20.123-05:00
workflow state
Published
tjohnson (Tenille Johnson)
Organism or Virus
organism
organism
Mus <mouse, genus>
Mammalia
Rodentia
Organism
non viral organism
Chordata
Vertebrata <Metazoa>
Glires
material_entity
independent_continuant
continuant
entity