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RFS-MycWT+/+/LSL-KrasG12D

eagle-i ID

http://ohsu.eagle-i.net/i/0000013b-4e79-7458-c825-3bd680000000

Resource Type

  1. Mus musculus

Properties

  1. Resource Description
    LSL-KrasG12D carry a latent point-mutant allele of Kras2 (K-rasG12D). Cre-mediated recombination leads to deletion of a transcriptional termination sequence (Lox-Stop-Lox) and expression of the oncogenic protein.
  2. Additional Name
    Rosa Floxed Stop-MycWT+/+/LSL-KrasG12D
  3. Related Disease
    cancer
  4. Related Publication or Documentation
    Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse.
  5. Website(s)
    http://mouse.ncifcrf.gov/available_details.asp?ID=01XJ6
  6. Parental Strain Name
    B6.129
  7. Parental Strain Name
    C57BL/6
  8. Genetic Alteration(s)
    LSL-KrasG12D
  9. Genetic Alteration(s)
    RFS-MycWT
  10. Developed by
    Sears, Rosalie, Ph.D.
  11. Location
    Rosalie Sears Laboratory
 
RDFRDF
 
Provenance Metadata About This Resource Record

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The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016