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B6.129-Kcnn1<tm1Jpad>/J

eagle-i ID

http://ohsu.eagle-i.net/i/0000013b-9166-42b5-c825-3bd680000000

Resource Type

  1. Mus musculus

Properties

  1. Resource Description
    "A loxP site was inserted 40 nucleotides 5' of the initiation methionine codon in exon 3 and a floxed neomycin resistance gene as well as an EGFP gene were inserted in the intron between exons 5 and 6. The EGFP insert was non functional. Cre mediated recombination removed the neo cassette leaving the loxP sites in exon 3 and intron 5 intact."
  2. Additional Name
    SK1-flox (3 loxP sites)
  3. Inventory Number
    JAX Stock No. 009591
  4. Related Disease
    neurodegenerative disease
  5. Related Publication or Documentation
    Small conductance Ca2+-activated K+ channel knock-out mice reveal the identity of calcium-dependent afterhyperpolarization currents.
  6. Related Publication or Documentation
    Kcnn1tm1.2Jpad genotyping protocol
  7. Website(s)
    http://jaxmice.jax.org/strain/009591.html
  8. Parental Strain Name
    C57BL/6J
  9. Biological process studied
    Potassium ion transport
  10. Biological process studied
    memory
  11. Genetic Alteration(s)
    Kcnn1[tm1.2Jpad]
  12. Developed by
    Adelman, John, PhD
  13. Phenotype Findings
    Null
  14. Location
    John Adelman laboratory
 
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Provenance Metadata About This Resource Record

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The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016