B6.129-Kcnn1<tm1Jpad>/J

eagle-i ID

Resource Type

Properties

1. Resource Description

   "A loxP site was inserted 40 nucleotides 5' of the initiation methionine codon in exon 3 and a floxed neomycin resistance gene as well as an EGFP gene were inserted in the intron between exons 5 and 6. The EGFP insert was non functional. Cre mediated recombination removed the neo cassette leaving the loxP sites in exon 3 and intron 5 intact."

2. Additional Name

   SK1-flox (3 loxP sites)

3. Inventory Number

   JAX Stock No. 009591

4. Related Disease

   neurodegenerative disease

5. Related Publication or Documentation

   Small conductance Ca2+-activated K+ channel knock-out mice reveal the identity of calcium-dependent afterhyperpolarization currents.

6. Related Publication or Documentation

   Kcnn1tm1.2Jpad genotyping protocol

7. Website(s)

   http://jaxmice.jax.org/strain/009591.html

8. Parental Strain Name

   C57BL/6J

9. Biological process studied

   Potassium ion transport

10. Biological process studied

    memory

11. Genetic Alteration(s)

    Kcnn1[tm1.2Jpad]

12. Developed by

    Adelman, John, PhD

13. Phenotype Findings

    Null

14. Location

    John Adelman laboratory