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129P3/J

eagle-i ID

http://ohsu.eagle-i.net/i/0000013c-8e65-7698-c825-3bd680000000

Resource Type

  1. Mus musculus

Properties

  1. Exchange facilitator
    <a href=http://jaxmice.jax.org/strain/000690.html target=_window><img src=https://eagle-i.net/images/jacksonlabs-button-large.png alt='Order from Jackson Laboratory'></a>
  2. Resource Description
    "Historically, the 129 inbred mice are known for the high incidence of spontaneous testicular teratomas, though the incidence differs between substrains. (1-3% in 129 parental substrains; 30% in teratoma substrains.) More recently, 129 mice are widely used in the production of targeted mutations due to the availability of multiple embryonic stem cell lines derived from them. There is major genetic variation within the 129 "family", which has led to an update of the nomenclature and a division of the substrains into three major groups: parental substrains (129P), steel substrains (129S) and "teratoma" substrains (129T). Investigators using 129 substrains for targeted mutagenesis should be careful in the selection of the appropriate 129 substrain to match the embryonic stem cell line."
  3. Inventory Number
    Jax Stock No. 000690
  4. Related Disease
    alcohol abuse
  5. Related Disease
    substance-related disorder
  6. Related Publication or Documentation
    Strain differences in behavioral inhibition in a Go/No-go task demonstrated using 15 inbred mouse strains.
  7. Parental Strain Name
    129P
  8. Phenotype Findings
    Age related hearing loss
  9. Location
    Suzanne Mitchell Laboratory
 
RDFRDF
 
Provenance Metadata About This Resource Record

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The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016