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A/HeJ
eagle-i ID
http://ohsu.eagle-i.net/i/0000013c-8e65-eb7e-c825-3bd680000000
Resource Type
Properties
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Exchange facilitator
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<a href=http://jaxmice.jax.org/strain/000645.html target=_window><img src=https://eagle-i.net/images/jacksonlabs-button-large.png alt='Order from Jackson Laboratory'></a>
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Resource Description
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"Developed by LC Strong in 1921 from a cross between a Cold Spring Harbor albino and a Bagg albino, the A inbred strain is used widely used in cancer and immunology research. It is highly susceptible to induction of congenital cleft palate by cortisone. It has a high incidence of spontaneous lung adenomas and lung tumors readily develop in response to carcinogens. High percentage of mammary adenocarcinomas (a large proportion acinar type) develop in multiparous females. Rare spontaneous myoepitheliomas arising from myoepithelial cells of various exocrine glands have been observed in The Jackson Laboratory substrains."
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Inventory Number
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Jax Stock No. 000645
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Related Disease
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alcohol abuse
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Related Disease
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substance-related disorder
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Related Publication or Documentation
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Strain differences in behavioral inhibition in a Go/No-go task demonstrated using 15 inbred mouse strains.
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Parental Strain Name
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BALB/cBy
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Location
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Suzanne Mitchell Laboratory