B6C3Fe a/a-Glra1spd/J

eagle-i ID

Resource Type

Properties

1. Resource Description

   The spasmodic mouse strain carries a single point mutation (A52S) in the α1 subunit of the glycine receptor (GlyR).

2. Inventory Number

   Jax Stock Number: 001278

3. Related Disease

   Stiff-Person syndrome

4. Website(s)

   http://jaxmice.jax.org/strain/001278.html

5. Parental Strain Name

   A/HeJ

6. Genetic Alteration(s)

   Single point mutation (A52S) in the α1 subunit of the glycine receptor (GlyR)

7. Phenotype Findings

   Homozygotes exhibit a constant tremor, an impaired righting reflex, and a tendency to walk tiptoe.

8. Location

   Bill Horton Laboratory

9. sameAs

   001278.html