eagle-i Oregon Health & Science UniversityOregon Health & Science University
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KI Fgfr3KO / TG Col2-pd2GFP

eagle-i ID

http://ohsu.eagle-i.net/i/0000013c-a716-be48-c825-3bd680000000

Resource Type

  1. Mus musculus

Properties

  1. Resource Description
    This strain is homozygous for the Col2-pd2GFP transgene and heterozygous for the Fgfr3 knockout allele.
  2. Related Disease
    bone disease
  3. Related Disease
    cartilage disease
  4. Genetic Alteration(s)
    Fgfr3 knockout
  5. Genetic Alteration(s)
    Col2-pd2GFP transgene
  6. Phenotype Findings
    KO heterozygotes show some skeletal overgrowth, but are essentially normal.
  7. Phenotype Findings
    The GFP transgene does not affect the phenotype.
  8. Phenotype Findings
    KO homozygotes exhibit an elongated skeletal eventually developing scoliosis and kiphosis.
  9. Location
    Bill Horton Laboratory
 
RDFRDF
 
Provenance Metadata About This Resource Record

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The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016