eagle-i Oregon Health & Science UniversityOregon Health & Science University
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eagle-i ID


Resource Type

  1. Mus musculus


  1. Resource Description
    This knockout strain is the result of a targeted disruption in Fgfr3.
  2. Related Disease
    bone disease
  3. Related Disease
    cartilage disease
  4. Genetic Alteration(s)
    Fgfr3 knockout
  5. Phenotype Findings
    KO heterozygotes show some skeletal overgrowth, but are essentially normal.
  6. Phenotype Findings
    KO homozygotes exhibit an elongated skeletal eventually developing scoliosis and kiphosis.
  7. Location
    Bill Horton Laboratory
Provenance Metadata About This Resource Record
Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016