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IL10-GFP
eagle-i ID
http://ohsu.eagle-i.net/i/0000013d-f073-ce49-f60f-bfff80000000
Resource Type
Properties
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Exchange facilitator
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<a href=http://jaxmice.jax.org/strain/008379.html target=_window><img src=http://eagle-i.net/images/jacksonlabs-button-large.png alt='Order from Jackson Laboratory'></a>
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Resource Description
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"This reporter strain may be used to detect and monitor cells committed to interleukin 10 (IL10) production. Green fluorescent protein knocked into the gene faithfully recapitulates normal expression patterns but is preferentially observed in some populations of the intestinal tissue. Expression assayed by fluorescent-activated cell sorting (FACS) has been detected after activation in macrophages and dendritic cells as well as intraintestinal lymphocytes and lamina propria lymphocytes. Targeted allele expression is slightly reduced, as compared to wild-type."
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Additional Name
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B6.129S6-Il10tm1Flv/J
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Inventory Number
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Jax Stock Number: 008379
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Related Disease
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cancer
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Parental Strain Name
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129S6/SvEvTac
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Genetic Alteration(s)
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Il10<tm1Flv>
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Location
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Lisa Coussens Laboratory