eagle-i Oregon Health & Science UniversityOregon Health & Science University
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IL10-GFP

eagle-i ID

http://ohsu.eagle-i.net/i/0000013d-f073-ce49-f60f-bfff80000000

Resource Type

  1. Mus musculus

Properties

  1. Exchange facilitator
    <a href=http://jaxmice.jax.org/strain/008379.html target=_window><img src=http://eagle-i.net/images/jacksonlabs-button-large.png alt='Order from Jackson Laboratory'></a>
  2. Resource Description
    "This reporter strain may be used to detect and monitor cells committed to interleukin 10 (IL10) production. Green fluorescent protein knocked into the gene faithfully recapitulates normal expression patterns but is preferentially observed in some populations of the intestinal tissue. Expression assayed by fluorescent-activated cell sorting (FACS) has been detected after activation in macrophages and dendritic cells as well as intraintestinal lymphocytes and lamina propria lymphocytes. Targeted allele expression is slightly reduced, as compared to wild-type."
  3. Additional Name
    B6.129S6-Il10tm1Flv/J
  4. Inventory Number
    Jax Stock Number: 008379
  5. Related Disease
    cancer
  6. Parental Strain Name
    129S6/SvEvTac
  7. Genetic Alteration(s)
    Il10<tm1Flv>
  8. Location
    Lisa Coussens Laboratory
 
RDFRDF
 
Provenance Metadata About This Resource Record

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The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016