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129S4-Trp53tm2Tyj
eagle-i ID
http://ohsu.eagle-i.net/i/0000013d-f07f-0fc7-f60f-bfff80000000
Resource Type
Properties
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Resource Description
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These mice contain a point-mutant allele of Trp53 that can be activated by Cre-mediated recombination. The conditional allele, containing LoxP sites and a transcriptional/translational STOP sequence, is functionally equivalent to a null mutation.
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Additional Name
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p53 LSL R172H
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Inventory Number
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Strain #: 01XM2
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Related Disease
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pancreatic cancer
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Website(s)
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http://mouse.ncifcrf.gov/available_details.asp?ID=01XM2
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Parental Strain Name
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129S4
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Genetic Alteration(s)
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Transformation related protein 53
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Developed by
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Jacks, Tyler
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Location
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Lisa Coussens Laboratory