eagle-i Oregon Health & Science UniversityOregon Health & Science University
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K14-HPV16

eagle-i ID

http://ohsu.eagle-i.net/i/0000013d-f07f-8a91-f60f-bfff80000000

Resource Type

  1. Mus musculus

Properties

  1. Resource Description
    "The transgene comprises the entire early coding sequence from wild-type human papillomavirus 16 (HPV16), extending from nucleotide (nt) 97 through nt 6152, flanked upstream by approximately 2 kilobases of DNA including the promoter/enhancer of the human keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner) gene and downstream by 500 base pairs derived from the 3' untranslated sequence of the same gene, including its polyadenylation signal. The keratin 14 promoter drives expression of the transgene in basal cells of the squamous epithelium."
  2. Related Disease
    skin cancer
  3. Website(s)
    http://www.informatics.jax.org/javawi2/servlet/WIFetch?page=alleleDetail&id=MGI:3047406
  4. Parental Strain Name
    (C57BL/6 x DBA/2)F2
  5. Genetic Alteration(s)
    Tg(KRT14-HPV16)wt1Dh
  6. Developed by
    0000013f-a0b6-59de-1581-ccbb80000000
  7. Location
    Lisa Coussens Laboratory
 
RDFRDF
 
Provenance Metadata About This Resource Record

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The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016