Rhesus macaque

eagle-i ID

Resource Type

Properties

1. Resource Description

   The Stouffer lab uses non-human primate models to investigate factors controlling the growth and ovulation of the mature follicle at midcycle, as well as development of the corpus luteum from the ovulatory follicle and its function until the end of the menstrual cycle or into early pregnancy. Additionally, they aim to study the reproductive neuroendocrine effects of androgen (testosterone, T) and Western-Style Diet (WSD) in female monkeys from peri-puberty to prime reproductive age

2. Related Disease

   ovarian disease

3. Related Disease

   hyperandrogenism

4. Related Publication or Documentation

   Elevated androgens during puberty in female rhesus monkeys lead to increased neuronal drive to the reproductive axis: a possible component of polycystic ovary syndrome

5. Related Publication or Documentation

   Amphiregulin promotes the maturation of oocytes isolated from the small antral follicles of the rhesus macaque.

6. Related Publication or Documentation

   Decorin is a part of the ovarian extracellular matrix in primates and may act as a signaling molecule.

7. Related Technique

   Immunohistochemistry assay

8. Related Technique

   Intracytoplasmic sperm injection (ICSI)

9. Related Technique

   Caspase assay

10. Related Technique

    Real-time PCR

11. Related Technique

    ELISA

12. Related Technique

    Western blot analysis

13. Biological process studied

    Reproduction

14. Biological process studied

    ovulation cycle process

15. Clinical or Environmental Source

    ONPRC

16. Location

    Richard Stouffer Laboratory