eagle-i Oregon Health & Science UniversityOregon Health & Science University
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Nude rats

eagle-i ID

http://ohsu.eagle-i.net/i/0000013f-440d-3997-f351-2c0e80000000

Resource Type

  1. Rattus norvegicus

Properties

  1. Resource Description
    Rat models are used for models of human brain tumors. All tumor models use nude rats housed in the animal facilities at OHSU Comparative Medicine. 1. Implanted primary brain tumors – caudate or cerebellum location Glioma (U87MG, UW28, U251) Medulloblastoma (DAOY, D283-Med) B-Cell lymphoma (MC116) Oligodendroglioma (Hs683) 2. Implanted metastatic brain tumors Breast cancer (MDA-MB231BR-HER2, and many other MDA-MB231BR clones with high or low HER2, GFP, fluc) Melanoma (A2058, A375) Lung cancer (LX-1 SCLC, H460 large cell NSCLC, A549 adenocarcinoma, H520 squamous cell) 3. Hematogenous brain metastases, cells infused into the internal carotid artery Breast cancer (MDA-MB231BR-HER2) Melanoma (A2058) Lung cancer (H460 large cell NSCLC, A549 adenocarcinoma) 4. Leptomeningeal tumors, cells infused into cerebral ventricle or cisterna magna Medulloblastoma (DAOY, D283-Med) Breast cancer (MDA-MB231BR-HER2) B-Cell lymphoma (MC116) 5. Intraperitoneal (abdominal cavity) Ovarian ( SKOV3) 6. Subcutaneous Neuroblastoma (SK-N-AS) Many of the cell lines listed above can grow SQ tumors.
  2. Related Disease
    medulloblastoma
  3. Related Disease
    brain cancer
  4. Related Disease
    lung cancer
  5. Related Disease
    breast cancer
  6. Related Disease
    melanoma
  7. Related Disease
    ovarian cancer
  8. Related Disease
    malignant glioma
  9. Related Disease
    oligodendroglioma
  10. Related Disease
    B-cell lymphoma
  11. Related Disease
    neuroblastoma
  12. Location
    Leslie Muldoon Laboratory
 
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