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Nude rats
eagle-i ID
http://ohsu.eagle-i.net/i/0000013f-440d-3997-f351-2c0e80000000
Resource Type
Properties
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Resource Description
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Rat models are used for models of human brain tumors. All tumor models use nude rats housed in the animal facilities at OHSU Comparative Medicine.
1. Implanted primary brain tumors – caudate or cerebellum location
Glioma (U87MG, UW28, U251)
Medulloblastoma (DAOY, D283-Med)
B-Cell lymphoma (MC116)
Oligodendroglioma (Hs683)
2. Implanted metastatic brain tumors
Breast cancer (MDA-MB231BR-HER2, and many other MDA-MB231BR clones with high or low HER2, GFP, fluc)
Melanoma (A2058, A375)
Lung cancer (LX-1 SCLC, H460 large cell NSCLC, A549 adenocarcinoma, H520 squamous cell)
3. Hematogenous brain metastases, cells infused into the internal carotid artery
Breast cancer (MDA-MB231BR-HER2)
Melanoma (A2058)
Lung cancer (H460 large cell NSCLC, A549 adenocarcinoma)
4. Leptomeningeal tumors, cells infused into cerebral ventricle or cisterna magna
Medulloblastoma (DAOY, D283-Med)
Breast cancer (MDA-MB231BR-HER2)
B-Cell lymphoma (MC116)
5. Intraperitoneal (abdominal cavity)
Ovarian ( SKOV3)
6. Subcutaneous
Neuroblastoma (SK-N-AS)
Many of the cell lines listed above can grow SQ tumors.
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Related Disease
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medulloblastoma
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Related Disease
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brain cancer
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Related Disease
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lung cancer
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Related Disease
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breast cancer
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Related Disease
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melanoma
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Related Disease
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ovarian cancer
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Related Disease
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malignant glioma
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Related Disease
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oligodendroglioma
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Related Disease
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B-cell lymphoma
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Related Disease
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neuroblastoma
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Location
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Leslie Muldoon Laboratory