eagle-i Oregon Health & Science UniversityOregon Health & Science University
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LV-Jagged1-HA plasmid

eagle-i ID


Resource Type

  1. Lentiviral plasmid


  1. Construct Insert
  2. Resource Description
    "cDNA containing the rat Jagged1-coding region fused to a sequence encoding a human influenza hemagglutinin (HA) epitope (kindly provided by Gerry Weinmaster; Department of Biological Chemistry, University of California, Los Angeles, CA) was inserted into the multiple cloning site of a LV vector. To restrict Jagged1 expression to oocytes, the cytomegalovirus promoter of this vector was replaced by the Gdf9 promoter (kindly provided by Austin Cooney; Baylor College of Medicine, Hous- ton, TX)."
  3. Construct Backbone
    LV vector
  4. Related Publication or Documentation
    Neurotrophins acting via TRKB receptors activate the JAGGED1-NOTCH2 cell-cell communication pathway to facilitate early ovarian development.
  5. Related Virus
  6. Location
    Sergio Ojeda Laboratory
Provenance Metadata About This Resource Record
Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016