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LV-Jagged1-HA plasmid
eagle-i ID
http://ohsu.eagle-i.net/i/0000013f-77db-2045-f351-2c0e80000000
Resource Type
Properties
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Construct Insert
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Jagged1
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Resource Description
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"cDNA containing the rat Jagged1-coding region fused to a sequence encoding a human influenza hemagglutinin (HA) epitope (kindly provided by Gerry Weinmaster; Department of Biological Chemistry, University of California, Los Angeles, CA) was inserted into the multiple cloning site of a LV vector. To restrict Jagged1 expression to oocytes, the cytomegalovirus promoter of this vector was replaced by the Gdf9 promoter (kindly provided by Austin Cooney; Baylor College of Medicine, Hous- ton, TX)."
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Construct Backbone
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LV vector
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Related Publication or Documentation
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Neurotrophins acting via TRKB receptors activate the JAGGED1-NOTCH2 cell-cell communication pathway to facilitate early ovarian development.
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Related Virus
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LV-Jagged1-HA
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Location
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Sergio Ojeda Laboratory