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Primate Pathology Laboratory

Summary:

The Pathology Services Unit (PSU) provides clinical and anatomic pathology support for disease diagnosis and surveillance for ONPRC’s animal resources.

Affiliations:

Resources:

Biological Specimens

  • Rhesus macaque tissue ( Biological Specimen )

    "The Tissue Distribution Program is administered through the Pathology Services Unit. Tissues are collected prospectively at the request of the recipient and according to the recipient’s protocol. Priority is given to OHSU investigators. Off campus investigators typically receive fresh tissue shipped overnight or frozen tissues shipped within 10 days of collection. Several types of tissues (including reproductive tracts, tisseeus from aged animals and liver as a source of genomic DNA) are collected and stored as a resource for distribution by other ONPRC cores. These tissues are collected and frozen by the Pathology Unit and transferred for storage and cataloging by the respective programs.

    The animals used for the Tissue Distribution Program are both investigator-assigned animals and colony assigned animals. The intent is to maximize the utilization of the limited nonhuman primate resource.

    The phenotypic data available for each tissue is extensive. Each animal receives a complete gross necropsy with histologic examination as appropriate (determined by the pathologist.) Gross necropsy includes complete visual examination of all organs and collection of organ weights. All of this information is linked to the animal’s individual record which includes signalment, source, geographic origin, medical and surgical history and reproductive history."

Services

  • Access to Macaque tissue for research projects ( Access service )

    "The Tissue Distribution Program is administered through the Pathology Services Unit. Tissues are collected prospectively at the request of the recipient and according to the recipient’s protocol. Priority is given to OHSU investigators. Off campus investigators typically receive fresh tissue shipped overnight or frozen tissues shipped within 10 days of collection. Several types of tissues (including reproductive tracts, tisseeus from aged animals and liver as a source of genomic DNA) are collected and stored as a resource for distribution by other ONPRC cores. These tissues are collected and frozen by the Pathology Unit and transferred for storage and cataloging by the respective programs.

    The animals used for the Tissue Distribution Program are both investigator-assigned animals and colony assigned animals. The intent is to maximize the utilization of the limited nonhuman primate resource.

    The phenotypic data available for each tissue is extensive. Each animal receives a complete gross necropsy with histologic examination as appropriate (determined by the pathologist.) Gross necropsy includes complete visual examination of all organs and collection of organ weights. All of this information is linked to the animal’s individual record which includes signalment, source, geographic origin, medical and surgical history and reproductive history."

  • Clinical and anatomic pathology support for disease diagnosis service ( Support service )

    "The Pathology Services Unit (PSU) provides clinical and anatomic pathology support for disease diagnosis and surveillance for ONPRC’s animal resources. It facilitates the research mission through provision of pathology support for investigators, and identification and characterization of unforeseen consequences of experimental protocols and participation in multidisciplinary research programs with clinicopathologic objectives. The Unit provides animal prosection, tissue collection and preparation services for ONPRC and collaborative investigators, and administers a nonhuman primate (NHP) Tissue Distribution Program (TDP) to maximize the availability and use of these tissues and minimize the number of NHPs required for research. Databases for normal body and organ weights are maintained to advance research with NHPs, and pathology databases relative to spontaneous diseases are maintained to facilitate identification and characterization of spontaneous NHP diseases potentially useful as animal models for biomedical research. Specialized training in NHP anatomic pathology is provided to students, fellows and visiting scientists."

  • Specialized training in nonhuman primate anatomic pathology ( Training service )


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Last updated: 2013-10-31T11:34:39.396-05:00

Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016