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Betsy Ferguson Laboratory

Summary:

The Oregon National Primate Research Center is one of 8 centers in the United States that supports non-human primate breeding and research. Our lab is committed to developing the genetic tools and resources necessary for the improved understanding of macaques, both in domestic breeding facilities and in international field settings. The current focus involves the use of single nucleotide polymorphisms (SNPs) for sub-species comparisons and for tracking phenotypes unique to certain populations.

We also have extensive medical histories of hundreds of captive rhesus macaques available to us. These records, in combination with the large family pedigrees produced within the breeding colonies, allow us to genetically analyze quantitative traits of interest. Currently we are studying traits commonly found in rhesus macaques, including macular degeneration, resistance to viral diseases, diabetes, as well a variety of behavioral traits. These research efforts involve interactive collaborations with numerous investigators, both at the OHSU and at other universities.

Affiliations:

People:

Resources:

Organisms and Viruses

  • Cebus albifrons ( Cebus albifrons )

    "We have extensive medical histories of hundreds of captive rhesus macaques available to us. These records, in combination with the large family pedigrees produced within the breeding colonies, allow us to genetically analyze quantitative traits of interest. Currently we are studying traits commonly found in rhesus macaques, including macular degeneration, resistance to viral diseases, diabetes, as well a variety of behavioral traits. These research efforts involve interactive collaborations with numerous investigators, both at the OHSU and at other universities."

  • Cebus apella ( Cebus apella )

    "We have extensive medical histories of hundreds of captive rhesus macaques available to us. These records, in combination with the large family pedigrees produced within the breeding colonies, allow us to genetically analyze quantitative traits of interest. Currently we are studying traits commonly found in rhesus macaques, including macular degeneration, resistance to viral diseases, diabetes, as well a variety of behavioral traits. These research efforts involve interactive collaborations with numerous investigators, both at the OHSU and at other universities."

  • Chlorocebus pygerythrus ( Chlorocebus pygerythrus )

    "We have extensive medical histories of hundreds of captive rhesus macaques available to us. These records, in combination with the large family pedigrees produced within the breeding colonies, allow us to genetically analyze quantitative traits of interest. Currently we are studying traits commonly found in rhesus macaques, including macular degeneration, resistance to viral diseases, diabetes, as well a variety of behavioral traits. These research efforts involve interactive collaborations with numerous investigators, both at the OHSU and at other universities."

  • Macaca arctoides ( Macaca arctoides )

    "We have extensive medical histories of hundreds of captive rhesus macaques available to us. These records, in combination with the large family pedigrees produced within the breeding colonies, allow us to genetically analyze quantitative traits of interest. Currently we are studying traits commonly found in rhesus macaques, including macular degeneration, resistance to viral diseases, diabetes, as well a variety of behavioral traits. These research efforts involve interactive collaborations with numerous investigators, both at the OHSU and at other universities."

  • Macaca fascicularis ( Macaca fascicularis )

    "We have extensive medical histories of hundreds of captive rhesus macaques available to us. These records, in combination with the large family pedigrees produced within the breeding colonies, allow us to genetically analyze quantitative traits of interest. Currently we are studying traits commonly found in rhesus macaques, including macular degeneration, resistance to viral diseases, diabetes, as well a variety of behavioral traits. These research efforts involve interactive collaborations with numerous investigators, both at the OHSU and at other universities."

  • Macaca fuscata ( Macaca fuscata )

    "We have extensive medical histories of hundreds of captive rhesus macaques available to us. These records, in combination with the large family pedigrees produced within the breeding colonies, allow us to genetically analyze quantitative traits of interest. Currently we are studying traits commonly found in rhesus macaques, including macular degeneration, resistance to viral diseases, diabetes, as well a variety of behavioral traits. These research efforts involve interactive collaborations with numerous investigators, both at the OHSU and at other universities."

  • Macaca mulatta ( Macaca mulatta )

    "We have extensive medical histories of hundreds of captive rhesus macaques available to us. These records, in combination with the large family pedigrees produced within the breeding colonies, allow us to genetically analyze quantitative traits of interest. Currently we are studying traits commonly found in rhesus macaques, including macular degeneration, resistance to viral diseases, diabetes, as well a variety of behavioral traits. These research efforts involve interactive collaborations with numerous investigators, both at the OHSU and at other universities."

  • Papio C. anubis ( Papio anubis )

Protocols

Services

  • Macaque ancestry SNP assay ( Material analysis service )

    Developed an assay to evaluate the ancestral origins of M. mulatta and M. fascicularis monkeys. The assay contains a collection of 96 unlinked, population-specific SNPs that can be used to characterize genetic diversity and to determine the likely ancestral composition of an animal.

  • VNTR analysis service ( Material analysis service )

    5HTT: Developed assays to genotype the serotonin transporter variable length polymorphism repeat (5HTT-LPR) in macaques.

    MAOA: Developed assays to genotype the monoamine oxidase A gene promoter length polymorphism repeat (MAOA-LPR) in macaques.


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Last updated: 2012-08-17T19:43:49.835-05:00

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