The Pacific Northwest Evidence-based Practice Center (EPC) conducts systematic reviews of health care topics for federal and state agencies, professional associations, and foundations. These reviews report the evidence from clinical research studies and the quality of that evidence for use by clinicians, employers, policymakers, researchers, and others in making decisions about the provision of health care services and health research. Reports may be used to inform the development of clinical practice guidelines, or to inform reimbursement and coverage policies. The Center is one of 11 EPCs sponsored by the Agency for Healthcare Research and Quality (AHRQ).
Investigators with the Pacific Northwest EPC have a particular interest in diagnostic technology assessment, prevention effectiveness, evidence-based informatics, research in managed care, and critical appraisal of cost-effectiveness analysis and decision analysis. In the past, faculty affiliated with the Center have investigated areas such as hepatitis C, pressure ulcers, acute head injury, pain management, drug effectiveness, thyroid function tests, cancer screening, diagnostic use of upper GI endoscopy, asthma diagnosis and management, telemedicine, menopausal symptoms, osteoporosis, vaginal birth after cesarean section, and statewide trauma systems. The Pacific Northwest EPC is housed in the Department of Medical Informatics & Clinical Epidemiology, OHSU School of Medicine, with partners at the University of Washington CHASE Alliance in Seattle, and Spectrum Research, Inc., in Tacoma, Washington.