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Jim Rosenbaum laboratory

Summary:

Dr. Rosenbaum's clinical interests include uveitis and autoimmune disease. His research interests include uveitis, cytokines, leukocyte and endothelial interactions. He currently heads the Uveitis Clinic and is the director of Inflammatory Research at OHSU. Dr. Rosenbaum is the Division Chief of Arthritis and Rheumatic Diseases. He is the Edward E. Rosenbaum Professor of Inflammatory Diseases. Dr. Rosenbaum received his medical degree in 1975 from Yale Medical School in New Haven, CT. He completed his Medicine residency and Rheumatology fellowship at Stanford Medical Center in Stanford, CA.

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Organisms and Viruses

  • CD11c-YFP ( Mus musculus )

    The promoter is used to drive expression of EYFP (Venus) in dendritic cells.

  • DO11.10 TCR transgenic ( Mus musculus )

    "Mice carrying the MHC class II restricted rearranged T cell receptor transgene, Tg(DO11.10)10Dlo, react to ovalbumin (OVA) peptide antigen. Intraperitoneal administration of OVA to transgenic mice results in a rapid deletion of the immature CD4+ CD8+ TCRlo thymocytes with progression to mature thymocytes. Apoptosis of cortical thymocytes within 20 hours of treatment indicates that apoptosis in important in the development of antigen-induced tolerance. Use of this rearranged T cell receptor transgene requires H2d background."

  • DsRed T-cell ( Mus musculus )

  • Foxp3-GFP ( Mus musculus )

  • Foxp3-GFP-DTR ( Mus musculus )

    Foxp3-GFP-DTR (human diphtheria toxin receptor) C57BL/6 mice allow elimination of Foxp3+ Treg by treatment with Dx (diphtheria toxin).

  • HLA-B27/human beta2-microglobulin ( Mus musculus )

  • IFNg KO ( Mus musculus )

  • IL-18 KO ( Mus musculus )

  • Lys-GFP ( Mus musculus )

  • S100A9 KO ( Mus musculus )

  • STAT1 KO ( Mus musculus )


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Last updated: 2012-12-12T20:16:47.397-06:00

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The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016