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Adk-Tg (fb-Adk-def)
eagle-i ID
http://ohsu.eagle-i.net/i/0000013f-782f-9858-f351-2c0e80000000
Resource Type
Mus musculus
Properties
Related Disease
Alzheimer's disease
Related Disease
Parkinson's disease
Related Disease
epilepsy syndrome
Related Disease
schizophrenia
Related Publication or Documentation
Adenosine kinase is a target for the prediction and prevention of epileptogenesis in mice.
Related Publication or Documentation
A ketogenic diet suppresses seizures in mice through adenosine A₁ receptors.
Related Publication or Documentation
Adenosine kinase determines the degree of brain injury after ischemic stroke in mice.
Related Publication or Documentation
Adenosine augmentation ameliorates psychotic and cognitive endophenotypes of schizophrenia.
Parental Strain Name
C57BL/6
Genetic Alteration(s)
Adenosine Kinase knockout
Genetic Alteration(s)
Adenosine kinase transgene (human ubiquitin promoter)
Phenotype Findings
Spontaneous electrographic seizures
Phenotype Findings
Cognitive impairment
Phenotype Findings
Reduced responsiveness to amphetamine
Phenotype Findings
Schizophrenia-related endophenotypes
Location
Detlev Boison Laboratory
Inferred Types from the eagle-i Ontology (
What is an ontology?
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entity
continuant
independent_continuant
material_entity
Organism
Mus <mouse, genus>
Glires
Mammalia
Chordata
Vertebrata <Metazoa>
Rodentia
Organism or Virus
Thing
Provenance Metadata About This Resource Record
workflow state
Published
contributor
nvasilevsky (Nicole Vasilevsky)
created
2013-06-24T16:57:51.842-05:00
creator
nvasilevsky (Nicole Vasilevsky)
modified
2013-06-24T17:13:14.109-05:00