Nuclear Magnetic Resonance Core Facility

Summary:

A facility that uses a state-of-the-art NMR spectrometer to verify or determine the structure of organic molecules. Housed in the Department of Physiology and Pharmacology, it is designed to exploit the power of designed small molecules as probes of protein and cellular function and to provide the foundation for the development of prototypic therapeutic agents.

Affiliations:

• Department of Physiology & Pharmacology

People:

• PI: Karpen, Jeffrey W., Ph.D.
  

Member: Banerji, Tapasree
Role: NMR Core Facility Manager, Research Associate

Resources:

Instruments

• Bruker Avance 400 spectrometer ( NMR instrument )
  

Services

• NMR instrument training ( Training service )
  

• Small molecule NMR analysis service ( Material analysis service )
  

  Most biologically-active small molecules can be studied, including: nucleotides, sugars and small polysaccharides, amino acids and small peptides, fatty acids, lipids, neurotransmitters, hormones, and most drugs.

Web Links:

• http://www.ohsu.edu/xd/education/schools/school-of-medicine/depar
  tments/basic-science-departments/physpharm/research/nmr-core.cfm