Three of the MARC's research components (5, 6, and 8) include experiments with lines of mice bred to have special genetic traits. The animal core supports these components by purchasing, testing, breeding, maintaining, and distributing these animals within the center.
The core will breed special mouse lines F1 and F2 that are descendents of C57BL/6J (B6) and DBA/2J (D2) inbred strains. For Components 5 and 6, the animal core will also produce independent sets of replicated mouse lines selected for high and low tendencies toward methamphetamine drinking and for high and low methamphetamine-induced sensitization.
In addition, the core is developing new behavioral-testing procedures and maintaining a database that will track individual animals and post their trait data for all MARC investigators to utilize.
Database is for tracking mouse identity and trait data for Methamphetamine Abuse Research Center (MARC) scientists for work on MARC Component Projects.
The core will breed special mouse lines F1 and F2 that are descendents of C57BL/6J (B6). The animal core will also produce independent sets of replicated mouse lines selected for high and low tendencies toward methamphetamine, drinking and for high and low methamphetamine-induced sensitization.
The core will breed special mouse lines F1 and F2 that are descendents of DBA/2J (D2). The animal core will also produce independent sets of replicated mouse lines selected for high and low tendencies toward methamphetamine, drinking and for high and low methamphetamine-induced sensitization.
Service is meant to assist MARC Researchers with mouse tests of methamphetamine consumption and methamphetamine sensitization. Assistance with experimental design, protocol, data handling is also available.
Service is for tracking mouse identity and trait data for Methamphetamine Abuse Research Center (MARC) scientists for work on MARC Component Projects.
"Three of the MARC's research components (5, 6, and 8) include experiments with lines of mice bred to have special genetic traits. The animal core supports these components by purchasing, testing, breeding, maintaining, and distributing these animals within the center.
The core will breed special mouse lines F1 and F2 that are descendents of C57BL/6J (B6) and DBA/2J (D2) inbred strains. For Components 5 and 6, the animal core will also produce independent sets of replicated mouse lines selected for high and low tendencies toward methamphetamine drinking and for high and low methamphetamine-induced sensitization.
In addition, the core is developing new behavioral-testing procedures and maintaining a database that will track individual animals and post their trait data for all MARC investigators to utilize."
Service includes assistance in purchasing mice for Methamphetamine Abuse Research Center (MARC) scientists for work in MARC Component Projects.
"The Animal Core will breed special mouse lines, F1 and F2 crosses that are descendents of C57BL/6J (B6) and DBA/2J (D2) inbred strains. For MARC Components 5 and 6, the animal core will also produce independent sets of replicated mouse lines selected for high and low tendencies toward methamphetamine drinking and for high and low methamphetamine-induced sensitization."
"The Animal Core will breed special mouse lines, from F2 crosses that are descendents of C57BL/6J (B6) and DBA/2J (D2) inbred strains. For MARC Components 5 and 6, the animal core will selectively breed independent sets of replicated mouse lines selected for high and low tendencies toward methamphetamine drinking and for high and low methamphetamine-induced sensitization."
"Three of the MARC's research components (5, 6, and 8) include experiments with lines of mice bred to have special genetic traits. The animal core supports these components by purchasing, testing, breeding, maintaining, and distributing these animals within the center.
The core will breed special mouse lines F1 and F2 that are descendents of C57BL/6J (B6) and DBA/2J (D2) inbred strains. For Components 5 and 6, the animal core will also produce independent sets of replicated mouse lines selected for high and low tendencies toward methamphetamine drinking and for high and low methamphetamine-induced sensitization.
In addition, the core is developing new behavioral-testing procedures and maintaining a database that will track individual animals and post their trait data for all MARC investigators to utilize."