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LAFT-1 mouse

eagle-i ID


Resource Type

  1. Mus musculus


  1. Resource Description
    Used to study alcoholism; acute functional tolerance to alcohol. Low Acute Functional Tolerance - 1. Embryo cryopreserved. Selectively bred line.
  2. Contact
    Metten, Pamela, Ph.D.
  3. Inventory Number
  4. Related Disease
    alcohol abuse
  5. Related Publication or Documentation
    Genetic Selection and Characterization of Mouse Lines for Acute Functional Tolerance to Ethanol
  6. Website(s)
  7. Website(s)
  8. Related Technique
    Behavioral assay
  9. Parental Strain Name
    HS/Ibg 8-way inbred strain cross
  10. Phenotype Findings
    Display low acute functional tolerance to ethanol, calculated as the difference in blood ethanol concentrations at the time of regaining the ability to stay for 1 minute on a stationary dowel (12.7 mm) after two consecutive injections of ethanol (1.75 g/ kg followed by 2.0 g/kg, IP).
  11. Location
    Portland Alcohol Research Center
Provenance Metadata About This Resource Record
Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016