RFS-myc[T58A]/Wap-cre

eagle-i ID

Resource Type

Properties

1. Resource Description

   Wap-cre mice express Cre in the secretory luminal and ductal epithelial cells of the mammary gland during late pregnancy and lactation.

2. Additional Name

   Rosa Floxed Stop-mycT58A/Wap-cre

3. Related Disease

   breast cancer

4. Related Publication or Documentation

   Phosphorylation regulates c-Myc’s oncogenic activity in the mammary gland

5. Website(s)

   http://mouse.ncifcrf.gov/available_details.asp?ID=01XA8

6. Parental Strain Name

   C57BL/6 

7. Genetic Alteration(s)

   Wap-cre

8. Genetic Alteration(s)

   RFS-MycT58A

9. Developed by

   Sears, Rosalie, Ph.D.

10. Phenotype Findings

    Expanded alveolar areas and the presence of enlarged ducts containing secretion

11. Location

    Rosalie Sears Laboratory